avianinfluenza.org

Trial of Experimental Avian Influenza Vaccine

Updated: Tuesday, October 23, 2018 11:23 AM EDT
Avian influenza Articles
Preparing for Human, H5N1 bird flu outbreak
Bird flu symptoms
Can you catch Bird Flu , Avian Influenza from eating poultry?
Confirmed human H5N1 bird flu cases
The origins of Bird Flu
Your cat and Bird flu , avian influenza
Potential bird flu treatment discovery
Bird flu , Avian influenza, new Spanish flu of 1918?
Bird Flu scare and the US bird Embargo
Bird flu , Avian Influenza a non-technical view
Bird flu , Avian flu outbreaks (human to human) in North America
Bird flu , Avian Influenza virus in Smuggled Thai Eagles
Bird flu , Avian Influenza Mutation H5N1 Virus
H5N1 Bird flu , Avian Influenza human vaccine developments
Bird flu , Avian influenza, fact or fiction?
Economic and Social Impacts of Bird Flu , Avian Influenza
Preparing For Pandemic Influenza
Bird Flu , Avian Influenza FAQ
Trial of Experimental Bird Flu , Avian Influenza Vaccine
Bird flu , Avian Influenza infection in Humans
Bird Flu , Avian Influenza explained

Bird Flu Map Links
USGS Interactive Bird flu map
Whooper Swan Tracking Map
Bird flu - US Government

Trial of Experimental Avian Influenza Vaccine

March 2005

Fast-track recruitment has begun for a trial to investigate the safety of a vaccine against the H5N1 strain of avian influenza, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced today.

Sites in Rochester, NY, Baltimore and Los Angeles will enroll a total of 450 healthy adults. The clinical sites are part of the NIAID-sponsored Vaccine and Treatment Evaluation Units (VTEU).

“While there have been relatively few cases worldwide of H5N1 avian influenza infection in humans, the public health community is concerned that the H5N1 strain of avian influenza virus will develop the capability of efficiently spreading from human to human and thus create a risk for a worldwide pandemic,” says NIAID Director Anthony S. Fauci, M.D.

“NIAID has supported research on H5N1, the strain responsible for this deadly form of avian influenza, since 1997 when the first cases in humans were reported. The initiation of this vaccine trial marks a key advance in our efforts to prepare to respond to an avian influenza pandemic,” adds Dr. Fauci.

Sanofi pasteur, Swiftwater, PA, manufactured the trial vaccine, which is an inactivated vaccine made from an H5N1 virus isolated in Southeast Asia in 2004. Sanofi pasteur, formerly Aventis Pasteur, was awarded a contract by NIAID to manufacture the H5N1 vaccine in May 2004.

This Phase I trial will test the avian influenza vaccine’s safety and ability to generate an immune response in 450 healthy adults aged 18 to 64. If the vaccine is shown to be safe in adults, there are plans to test it in other populations, such as the elderly and children.

H5N1 avian influenza leads to severe disease in both birds and humans. Between January 2004 and March 11, 2005, there were 69 confirmed cases of and 46 deaths from H5N1 infection in humans reported to the World Health Organization. To date, there has been a small number of cases where human-to-human transmission of the virus may have occurred. However, public health experts fear that the virus may evolve into one that is more easily transmitted between people. If this were to happen, a worldwide pandemic could follow.

Influenza pandemics are global outbreaks that emerge infrequently and unpredictably and involve strains of virus to which humans have little or no immunity. H5N1 is one such Avian Influenza virus strain. The last influenza pandemic swept the globe in 1968; many public health officials believe the world is overdue for another one

Mild form of bird flu found in Minnesota turkey flock - DesMoinesRegister.com
23 Oct 2018 at 10:17am
Mild form of bird flu found in Minnesota turkey flock - DesMoinesRegister.com
23 Oct 2018 at 10:17am
Mild form of bird flu found in Minnesota turkey flock - KWWL - kwwl.com
23 Oct 2018 at 8:57am
Mild form of bird flu found in Minnesota turkey flock - KWWL - kwwl.com
23 Oct 2018 at 8:57am
Bulgaria's Food Safety Agency: No Danger to Consumers Amid Bird Flu Outbreaks...
23 Oct 2018 at 1:10am
Bulgaria's Food Safety Agency: No Danger to Consumers Amid Bird Flu Outbreaks...
23 Oct 2018 at 1:10am
Korea strengthens bird flu quarantine efforts ahead of winter - The Korea Herald
22 Oct 2018 at 7:06pm
Korea strengthens bird flu quarantine efforts ahead of winter - The Korea Herald
22 Oct 2018 at 7:06pm
S. Korea strengthens bird flu quarantine efforts ahead of winter - Yonhap News
22 Oct 2018 at 7:02pm
S. Korea strengthens bird flu quarantine efforts ahead of winter - Yonhap News
22 Oct 2018 at 7:02pm
Bulgaria reports bird flu outbreak on two farms in south of the country - Ukr...
20 Oct 2018 at 8:45am
Bulgaria reports bird flu outbreak on two farms in south of the country - Ukr...
20 Oct 2018 at 8:45am
Bird flu outbreak reported in Bulgaria - Xinhua
19 Oct 2018 at 7:04am
Bird flu outbreak reported in Bulgaria - Xinhua
19 Oct 2018 at 7:04am
Bulgaria reports bird flu outbreak on two farms - Independent.ie
18 Oct 2018 at 10:09pm
Bulgaria reports bird flu outbreak on two farms - Independent.ie
18 Oct 2018 at 10:09pm
French foie gras makers say they are ready if bird flu returns - Reuters
18 Oct 2018 at 9:33am
French foie gras makers say they are ready if bird flu returns - Reuters
18 Oct 2018 at 9:33am
Bulgaria reports bird flu outbreak on two farms in south - Reuters
18 Oct 2018 at 8:32am
Bulgaria reports bird flu outbreak on two farms in south - Reuters
18 Oct 2018 at 8:32am
VN reports no new cases of bird flu in humans since 2014 - Viet Nam News
17 Oct 2018 at 1:00am
VN reports no new cases of bird flu in humans since 2014 - Viet Nam News
17 Oct 2018 at 1:00am
Over 760 billion VND for bird flu control during 2019-2025 - http://en.vietna...
16 Oct 2018 at 5:52am
Over 760 billion VND for bird flu control during 2019-2025 - http://en.vietna...
16 Oct 2018 at 5:52am
Egypt to bar live poultry trade over bird flu fears - Egypt Independent
11 Oct 2018 at 7:29am
Egypt to bar live poultry trade over bird flu fears - Egypt Independent
11 Oct 2018 at 7:29am
China reports new H5N6 bird flu outbreak in Hunan province - Channel NewsAsia
9 Oct 2018 at 3:46am
China reports new H5N6 bird flu outbreak in Hunan province - Channel NewsAsia
9 Oct 2018 at 3:46am
Bird flu detected at poultry farm in southern Bulgaria - Reuters
5 Oct 2018 at 1:49am
Bird flu detected at poultry farm in southern Bulgaria - Reuters
5 Oct 2018 at 1:49am
China reports H5N6 bird flu case on poultry farm in Guizhou province - Reuters
29 Sep 2018 at 3:16am
China reports H5N6 bird flu case on poultry farm in Guizhou province - Reuters
29 Sep 2018 at 3:16am
After chicken, bird flu virus emerges in ducks in China - Medibulletin
28 Sep 2018 at 6:41am
After chicken, bird flu virus emerges in ducks in China - Medibulletin
28 Sep 2018 at 6:41am
Bird flu switches from chickens to ducks - Cosmos
27 Sep 2018 at 8:00am
Bird flu switches from chickens to ducks - Cosmos
27 Sep 2018 at 8:00am
Thailand considers jail for feeding pigeons to eliminate bird flu risk - Time...
26 Sep 2018 at 6:19am
Thailand considers jail for feeding pigeons to eliminate bird flu risk - Time...
26 Sep 2018 at 6:19am
Bird Flu Threatens Innscor Profits - pindula.co.zw
24 Sep 2018 at 1:41pm
Bird Flu Threatens Innscor Profits - pindula.co.zw
24 Sep 2018 at 1:41pm