avianinfluenza.org

Trial of Experimental Avian Influenza Vaccine

Updated: Sunday, June 20, 2021 2:22 PM EDT
Avian influenza Articles
Preparing for Human, H5N1 bird flu outbreak
Bird flu symptoms
Can you catch Bird Flu , Avian Influenza from eating poultry?
Confirmed human H5N1 bird flu cases
The origins of Bird Flu
Your cat and Bird flu , avian influenza
Potential bird flu treatment discovery
Bird flu , Avian influenza, new Spanish flu of 1918?
Bird Flu scare and the US bird Embargo
Bird flu , Avian Influenza a non-technical view
Bird flu , Avian flu outbreaks (human to human) in North America
Bird flu , Avian Influenza virus in Smuggled Thai Eagles
Bird flu , Avian Influenza Mutation H5N1 Virus
H5N1 Bird flu , Avian Influenza human vaccine developments
Bird flu , Avian influenza, fact or fiction?
Economic and Social Impacts of Bird Flu , Avian Influenza
Preparing For Pandemic Influenza
Bird Flu , Avian Influenza FAQ
Trial of Experimental Bird Flu , Avian Influenza Vaccine
Bird flu , Avian Influenza infection in Humans
Bird Flu , Avian Influenza explained

Bird Flu Map Links
USGS Interactive Bird flu map
Whooper Swan Tracking Map
Bird flu - US Government

Trial of Experimental Avian Influenza Vaccine

March 2005

Fast-track recruitment has begun for a trial to investigate the safety of a vaccine against the H5N1 strain of avian influenza, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced today.

Sites in Rochester, NY, Baltimore and Los Angeles will enroll a total of 450 healthy adults. The clinical sites are part of the NIAID-sponsored Vaccine and Treatment Evaluation Units (VTEU).

“While there have been relatively few cases worldwide of H5N1 avian influenza infection in humans, the public health community is concerned that the H5N1 strain of avian influenza virus will develop the capability of efficiently spreading from human to human and thus create a risk for a worldwide pandemic,” says NIAID Director Anthony S. Fauci, M.D.

“NIAID has supported research on H5N1, the strain responsible for this deadly form of avian influenza, since 1997 when the first cases in humans were reported. The initiation of this vaccine trial marks a key advance in our efforts to prepare to respond to an avian influenza pandemic,” adds Dr. Fauci.

Sanofi pasteur, Swiftwater, PA, manufactured the trial vaccine, which is an inactivated vaccine made from an H5N1 virus isolated in Southeast Asia in 2004. Sanofi pasteur, formerly Aventis Pasteur, was awarded a contract by NIAID to manufacture the H5N1 vaccine in May 2004.

This Phase I trial will test the avian influenza vaccine’s safety and ability to generate an immune response in 450 healthy adults aged 18 to 64. If the vaccine is shown to be safe in adults, there are plans to test it in other populations, such as the elderly and children.

H5N1 avian influenza leads to severe disease in both birds and humans. Between January 2004 and March 11, 2005, there were 69 confirmed cases of and 46 deaths from H5N1 infection in humans reported to the World Health Organization. To date, there has been a small number of cases where human-to-human transmission of the virus may have occurred. However, public health experts fear that the virus may evolve into one that is more easily transmitted between people. If this were to happen, a worldwide pandemic could follow.

Influenza pandemics are global outbreaks that emerge infrequently and unpredictably and involve strains of virus to which humans have little or no immunity. H5N1 is one such Avian Influenza virus strain. The last influenza pandemic swept the globe in 1968; many public health officials believe the world is overdue for another one

China reports outbreak of H5N8 bird flu in wild birds - The Poultry Site
10 Jun 2021 at 12:00am
China reports outbreak of H5N8 bird flu in wild birds - The Poultry Site
10 Jun 2021 at 12:00am
Bird flu strain found in three Free State poultry farms - SABC News
9 Jun 2021 at 5:51am
Bird flu strain found in three Free State poultry farms - SABC News
9 Jun 2021 at 5:51am
Poultry disease infects 250,000 birds in Northern Ireland - BBC News
8 Jun 2021 at 12:00am
Poultry disease infects 250,000 birds in Northern Ireland - BBC News
8 Jun 2021 at 12:00am
3 Free State farms confirm bird flu outbreaks - East Coast Radio
8 Jun 2021 at 12:00am
3 Free State farms confirm bird flu outbreaks - East Coast Radio
8 Jun 2021 at 12:00am
Is a new bird flu the next pandemic? | TheHill - The Hill
8 Jun 2021 at 12:00am
Is a new bird flu the next pandemic? | TheHill - The Hill
8 Jun 2021 at 12:00am
Egypt denies emergence of new bird flu strain - Arab News
7 Jun 2021 at 7:03am
Egypt denies emergence of new bird flu strain - Arab News
7 Jun 2021 at 7:03am
Egypt denies all claims of H10 bird flu virus in country - Egypt Independent
6 Jun 2021 at 4:48am
Egypt denies all claims of H10 bird flu virus in country - Egypt Independent
6 Jun 2021 at 4:48am
Explained | What does the World Health Organisation say about H10N3 bird flu,...
6 Jun 2021 at 12:00am
Explained | What does the World Health Organisation say about H10N3 bird flu,...
6 Jun 2021 at 12:00am
Weekly poultry digest: China reports a human case of bird flu - The Poultry Site
4 Jun 2021 at 12:00am
Weekly poultry digest: China reports a human case of bird flu - The Poultry Site
4 Jun 2021 at 12:00am
First human case of H10N3 influenza reported in Jiangsu, China - News-Medical...
4 Jun 2021 at 12:00am
First human case of H10N3 influenza reported in Jiangsu, China - News-Medical...
4 Jun 2021 at 12:00am
China confirms world's first human case of H10N3 bird flu but says it's highl...
3 Jun 2021 at 12:00am
China confirms world's first human case of H10N3 bird flu but says it's highl...
3 Jun 2021 at 12:00am
Africa's last penguins could be vaccinated against bird flu in last-ditch att...
2 Jun 2021 at 12:00am
Africa's last penguins could be vaccinated against bird flu in last-ditch att...
2 Jun 2021 at 12:00am
Agriculture ensures China's bird flu will not affect here - Dominican Today
2 Jun 2021 at 12:00am
Agriculture ensures China's bird flu will not affect here - Dominican Today
2 Jun 2021 at 12:00am
China reports human case of H10N3 bird flu - BusinessLine
1 Jun 2021 at 12:00am
China reports human case of H10N3 bird flu - BusinessLine
1 Jun 2021 at 12:00am
China reports first human patient of H10N3 bird flu strain - UPI News
1 Jun 2021 at 12:00am
China reports first human patient of H10N3 bird flu strain - UPI News
1 Jun 2021 at 12:00am
China reports first human case of H10N3 bird flu - Reuters
1 Jun 2021 at 12:00am
China reports first human case of H10N3 bird flu - Reuters
1 Jun 2021 at 12:00am
Highly pathogenic bird flu outbreak hits 46 countries - ZME Science
28 May 2021 at 12:00am
Highly pathogenic bird flu outbreak hits 46 countries - ZME Science
28 May 2021 at 12:00am
Scientists have trained ferrets to sniff out bird flu virus in duck poo - ABC...
26 May 2021 at 12:00am
Scientists have trained ferrets to sniff out bird flu virus in duck poo - ABC...
26 May 2021 at 12:00am
H5N8 avian flu emerges as next public health concern - BioWorld Online
25 May 2021 at 12:00am
H5N8 avian flu emerges as next public health concern - BioWorld Online
25 May 2021 at 12:00am
Be alert to pandemic risk after Russia bird flu cases, say Chinese experts - ...
25 May 2021 at 12:00am
Be alert to pandemic risk after Russia bird flu cases, say Chinese experts - ...
25 May 2021 at 12:00am