avianinfluenza.org

Trial of Experimental Avian Influenza Vaccine

Updated: Thursday, February 25, 2021 11:42 AM EDT
Avian influenza Articles
Preparing for Human, H5N1 bird flu outbreak
Bird flu symptoms
Can you catch Bird Flu , Avian Influenza from eating poultry?
Confirmed human H5N1 bird flu cases
The origins of Bird Flu
Your cat and Bird flu , avian influenza
Potential bird flu treatment discovery
Bird flu , Avian influenza, new Spanish flu of 1918?
Bird Flu scare and the US bird Embargo
Bird flu , Avian Influenza a non-technical view
Bird flu , Avian flu outbreaks (human to human) in North America
Bird flu , Avian Influenza virus in Smuggled Thai Eagles
Bird flu , Avian Influenza Mutation H5N1 Virus
H5N1 Bird flu , Avian Influenza human vaccine developments
Bird flu , Avian influenza, fact or fiction?
Economic and Social Impacts of Bird Flu , Avian Influenza
Preparing For Pandemic Influenza
Bird Flu , Avian Influenza FAQ
Trial of Experimental Bird Flu , Avian Influenza Vaccine
Bird flu , Avian Influenza infection in Humans
Bird Flu , Avian Influenza explained

Bird Flu Map Links
USGS Interactive Bird flu map
Whooper Swan Tracking Map
Bird flu - US Government

Trial of Experimental Avian Influenza Vaccine

March 2005

Fast-track recruitment has begun for a trial to investigate the safety of a vaccine against the H5N1 strain of avian influenza, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced today.

Sites in Rochester, NY, Baltimore and Los Angeles will enroll a total of 450 healthy adults. The clinical sites are part of the NIAID-sponsored Vaccine and Treatment Evaluation Units (VTEU).

“While there have been relatively few cases worldwide of H5N1 avian influenza infection in humans, the public health community is concerned that the H5N1 strain of avian influenza virus will develop the capability of efficiently spreading from human to human and thus create a risk for a worldwide pandemic,” says NIAID Director Anthony S. Fauci, M.D.

“NIAID has supported research on H5N1, the strain responsible for this deadly form of avian influenza, since 1997 when the first cases in humans were reported. The initiation of this vaccine trial marks a key advance in our efforts to prepare to respond to an avian influenza pandemic,” adds Dr. Fauci.

Sanofi pasteur, Swiftwater, PA, manufactured the trial vaccine, which is an inactivated vaccine made from an H5N1 virus isolated in Southeast Asia in 2004. Sanofi pasteur, formerly Aventis Pasteur, was awarded a contract by NIAID to manufacture the H5N1 vaccine in May 2004.

This Phase I trial will test the avian influenza vaccine’s safety and ability to generate an immune response in 450 healthy adults aged 18 to 64. If the vaccine is shown to be safe in adults, there are plans to test it in other populations, such as the elderly and children.

H5N1 avian influenza leads to severe disease in both birds and humans. Between January 2004 and March 11, 2005, there were 69 confirmed cases of and 46 deaths from H5N1 infection in humans reported to the World Health Organization. To date, there has been a small number of cases where human-to-human transmission of the virus may have occurred. However, public health experts fear that the virus may evolve into one that is more easily transmitted between people. If this were to happen, a worldwide pandemic could follow.

Influenza pandemics are global outbreaks that emerge infrequently and unpredictably and involve strains of virus to which humans have little or no immunity. H5N1 is one such Avian Influenza virus strain. The last influenza pandemic swept the globe in 1968; many public health officials believe the world is overdue for another one

Pigeons found dead in Srinagar's Chatabal as bird flu worsens - The Kashmir W...
25 Feb 2021 at 9:31am
Pigeons found dead in Srinagar's Chatabal as bird flu worsens - The Kashmir W...
25 Feb 2021 at 9:31am
Bird flu sparks egg shortages in South Korea - Poultry World
25 Feb 2021 at 8:51am
Bird flu sparks egg shortages in South Korea - Poultry World
25 Feb 2021 at 8:51am
First Human Cases of Bird Flu Strain Detected in Russia - One Green Planet
25 Feb 2021 at 8:09am
First Human Cases of Bird Flu Strain Detected in Russia - One Green Planet
25 Feb 2021 at 8:09am
Bird Flu: HC asks Nandurbar authorities to consider all aspects before taking...
25 Feb 2021 at 7:53am
Bird Flu: HC asks Nandurbar authorities to consider all aspects before taking...
25 Feb 2021 at 7:53am
Russia reports first-ever cases of H5N8 bird flu in humans - Totally Vegan Buzz
25 Feb 2021 at 5:34am
Russia reports first-ever cases of H5N8 bird flu in humans - Totally Vegan Buzz
25 Feb 2021 at 5:34am
Afghanistan reports H5N8 bird flu on farm - OIE - Successful Farming
25 Feb 2021 at 4:30am
Afghanistan reports H5N8 bird flu on farm - OIE - Successful Farming
25 Feb 2021 at 4:30am
Bird flu: 45 chickens found dead in Palghar - Mumbai Mirror
24 Feb 2021 at 11:41pm
Bird flu: 45 chickens found dead in Palghar - Mumbai Mirror
24 Feb 2021 at 11:41pm
S. Korea reports another highly pathogenic bird flu case, total now at 102 - ...
24 Feb 2021 at 6:30pm
S. Korea reports another highly pathogenic bird flu case, total now at 102 - ...
24 Feb 2021 at 6:30pm
Bird flu confirmed in Maharashtra?s Palghar, says deputy collector - Hindusta...
24 Feb 2021 at 5:58am
Bird flu confirmed in Maharashtra?s Palghar, says deputy collector - Hindusta...
24 Feb 2021 at 5:58am
S. Korea investigating new suspected bird flu case, total now at 101 - The Ko...
23 Feb 2021 at 6:33pm
S. Korea investigating new suspected bird flu case, total now at 101 - The Ko...
23 Feb 2021 at 6:33pm
Second outbreak of bird flu confirmed in Stanley Park after swan falls ill an...
23 Feb 2021 at 7:50am
Second outbreak of bird flu confirmed in Stanley Park after swan falls ill an...
23 Feb 2021 at 7:50am
Bird flu outbreak strikes again; domestic fowl keepers urged to keep birds in...
23 Feb 2021 at 4:42am
Bird flu outbreak strikes again; domestic fowl keepers urged to keep birds in...
23 Feb 2021 at 4:42am
Pong Wetland Wildlife Sanctuary opens for visitors after bird flu outbreak - ...
23 Feb 2021 at 4:22am
Pong Wetland Wildlife Sanctuary opens for visitors after bird flu outbreak - ...
23 Feb 2021 at 4:22am
Egg supply tightens in Poland as EU bird flu crisis hits industry - Successfu...
23 Feb 2021 at 2:36am
Egg supply tightens in Poland as EU bird flu crisis hits industry - Successfu...
23 Feb 2021 at 2:36am
Mohali district rid of bird flu, says DC - Times of India
22 Feb 2021 at 10:22pm
Mohali district rid of bird flu, says DC - Times of India
22 Feb 2021 at 10:22pm
The Bird Flu Virus That Has Infected People in Russia - Bloomberg
22 Feb 2021 at 7:32pm
The Bird Flu Virus That Has Infected People in Russia - Bloomberg
22 Feb 2021 at 7:32pm
Punjab: Area near Alipur Naggal wetlands declared infected with bird flu - Th...
22 Feb 2021 at 1:24pm
Punjab: Area near Alipur Naggal wetlands declared infected with bird flu - Th...
22 Feb 2021 at 1:24pm
Estonian Health Board: Risk of human-to-human transmission of bird flu low - ...
22 Feb 2021 at 11:22am
Estonian Health Board: Risk of human-to-human transmission of bird flu low - ...
22 Feb 2021 at 11:22am
Suspected case of bird flu found in S. Korea - Yonhap News
22 Feb 2021 at 6:32am
Suspected case of bird flu found in S. Korea - Yonhap News
22 Feb 2021 at 6:32am
Bird flu impact: Chicken prices still low in Maharashtra, though consumption ...
22 Feb 2021 at 6:10am
Bird flu impact: Chicken prices still low in Maharashtra, though consumption ...
22 Feb 2021 at 6:10am