avianinfluenza.org

Trial of Experimental Avian Influenza Vaccine

Updated: Friday, October 20, 2017 1:45 AM EDT
Avian influenza Articles
Preparing for Human, H5N1 bird flu outbreak
Bird flu symptoms
Can you catch Bird Flu , Avian Influenza from eating poultry?
Confirmed human H5N1 bird flu cases
The origins of Bird Flu
Your cat and Bird flu , avian influenza
Potential bird flu treatment discovery
Bird flu , Avian influenza, new Spanish flu of 1918?
Bird Flu scare and the US bird Embargo
Bird flu , Avian Influenza a non-technical view
Bird flu , Avian flu outbreaks (human to human) in North America
Bird flu , Avian Influenza virus in Smuggled Thai Eagles
Bird flu , Avian Influenza Mutation H5N1 Virus
H5N1 Bird flu , Avian Influenza human vaccine developments
Bird flu , Avian influenza, fact or fiction?
Economic and Social Impacts of Bird Flu , Avian Influenza
Preparing For Pandemic Influenza
Bird Flu , Avian Influenza FAQ
Trial of Experimental Bird Flu , Avian Influenza Vaccine
Bird flu , Avian Influenza infection in Humans
Bird Flu , Avian Influenza explained

Bird Flu Map Links
USGS Interactive Bird flu map
Whooper Swan Tracking Map
Bird flu - US Government

Trial of Experimental Avian Influenza Vaccine

March 2005

Fast-track recruitment has begun for a trial to investigate the safety of a vaccine against the H5N1 strain of avian influenza, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced today.

Sites in Rochester, NY, Baltimore and Los Angeles will enroll a total of 450 healthy adults. The clinical sites are part of the NIAID-sponsored Vaccine and Treatment Evaluation Units (VTEU).

“While there have been relatively few cases worldwide of H5N1 avian influenza infection in humans, the public health community is concerned that the H5N1 strain of avian influenza virus will develop the capability of efficiently spreading from human to human and thus create a risk for a worldwide pandemic,” says NIAID Director Anthony S. Fauci, M.D.

“NIAID has supported research on H5N1, the strain responsible for this deadly form of avian influenza, since 1997 when the first cases in humans were reported. The initiation of this vaccine trial marks a key advance in our efforts to prepare to respond to an avian influenza pandemic,” adds Dr. Fauci.

Sanofi pasteur, Swiftwater, PA, manufactured the trial vaccine, which is an inactivated vaccine made from an H5N1 virus isolated in Southeast Asia in 2004. Sanofi pasteur, formerly Aventis Pasteur, was awarded a contract by NIAID to manufacture the H5N1 vaccine in May 2004.

This Phase I trial will test the avian influenza vaccine’s safety and ability to generate an immune response in 450 healthy adults aged 18 to 64. If the vaccine is shown to be safe in adults, there are plans to test it in other populations, such as the elderly and children.

H5N1 avian influenza leads to severe disease in both birds and humans. Between January 2004 and March 11, 2005, there were 69 confirmed cases of and 46 deaths from H5N1 infection in humans reported to the World Health Organization. To date, there has been a small number of cases where human-to-human transmission of the virus may have occurred. However, public health experts fear that the virus may evolve into one that is more easily transmitted between people. If this were to happen, a worldwide pandemic could follow.

Influenza pandemics are global outbreaks that emerge infrequently and unpredictably and involve strains of virus to which humans have little or no immunity. H5N1 is one such Avian Influenza virus strain. The last influenza pandemic swept the globe in 1968; many public health officials believe the world is overdue for another one

The next wave of bird flu could be worse than ever - Science News
19 Oct 2017 at 11:37am
The next wave of bird flu could be worse than ever - Science News
19 Oct 2017 at 11:37am
Western Cape counts the cost of drought and bird flu - Farmer's Weekly
19 Oct 2017 at 7:41am
Western Cape counts the cost of drought and bird flu - Farmer's Weekly
19 Oct 2017 at 7:41am
Bird flu: higher egg prices and shortages loom - Kempton Express
18 Oct 2017 at 9:17pm
Bird flu: higher egg prices and shortages loom - Kempton Express
18 Oct 2017 at 9:17pm
Reps want N1.8bn compensation for bird flu victims - Daily Trust
18 Oct 2017 at 6:03pm
Reps want N1.8bn compensation for bird flu victims - Daily Trust
18 Oct 2017 at 6:03pm
Dutch bird flu outbreak leads to trade bans - Poultry World
18 Oct 2017 at 4:14am
Dutch bird flu outbreak leads to trade bans - Poultry World
18 Oct 2017 at 4:14am
[LISTEN] Eggs shortage to worsen amid bird flu outbreak - Eyewitness News
17 Oct 2017 at 10:41pm
[LISTEN] Eggs shortage to worsen amid bird flu outbreak - Eyewitness News
17 Oct 2017 at 10:41pm
No decision yet on bird flu vaccination - Zokwana - Fin24
17 Oct 2017 at 10:35pm
No decision yet on bird flu vaccination - Zokwana - Fin24
17 Oct 2017 at 10:35pm
Widespread bird flu, drought affect W Cape farmers - eNCA (blog)
17 Oct 2017 at 8:45pm
Widespread bird flu, drought affect W Cape farmers - eNCA (blog)
17 Oct 2017 at 8:45pm
South Korean egg prices back down after bird flu spike - Nikkei Asian Review
17 Oct 2017 at 6:11pm
South Korean egg prices back down after bird flu spike - Nikkei Asian Review
17 Oct 2017 at 6:11pm
China confirms bird flu outbreak at poultry farms in central province - Nasdaq
17 Oct 2017 at 3:39am
China confirms bird flu outbreak at poultry farms in central province - Nasdaq
17 Oct 2017 at 3:39am
Farmers voice concerns about compensation for bird flu - Poultry World
16 Oct 2017 at 5:31am
Farmers voice concerns about compensation for bird flu - Poultry World
16 Oct 2017 at 5:31am
Poultry sector close to full recovery from bird flu - Philippine Star
15 Oct 2017 at 9:31am
Poultry sector close to full recovery from bird flu - Philippine Star
15 Oct 2017 at 9:31am
New bird flu text alert service in NI - Irish Farmers Journal
15 Oct 2017 at 7:16am
New bird flu text alert service in NI - Irish Farmers Journal
15 Oct 2017 at 7:16am
New bird flu case in Netherlands; 42000 egg-laying hens culled - NL Times
13 Oct 2017 at 6:10am
New bird flu case in Netherlands; 42000 egg-laying hens culled - NL Times
13 Oct 2017 at 6:10am
WC govt, DAFF working to find solutions to bird flu outbreak - Eyewitness News
13 Oct 2017 at 12:21am
WC govt, DAFF working to find solutions to bird flu outbreak - Eyewitness News
13 Oct 2017 at 12:21am
Bird flu cases in WC increases to 50 - Eyewitness News
12 Oct 2017 at 9:52am
Bird flu cases in WC increases to 50 - Eyewitness News
12 Oct 2017 at 9:52am
Zambia has not recorded any cases of bird flu-Katambo - Lusaka Times
12 Oct 2017 at 9:18am
Zambia has not recorded any cases of bird flu-Katambo - Lusaka Times
12 Oct 2017 at 9:18am
Producers to boost biosecurity measures after bird flu outbreak - Fin24
12 Oct 2017 at 7:40am
Producers to boost biosecurity measures after bird flu outbreak - Fin24
12 Oct 2017 at 7:40am
Some WC retailers running out of eggs due to bird flu - Eyewitness News
11 Oct 2017 at 11:10am
Some WC retailers running out of eggs due to bird flu - Eyewitness News
11 Oct 2017 at 11:10am
'Devastating' bird flu culling to cost Gauteng farm R65m - Fin24
11 Oct 2017 at 1:46am
'Devastating' bird flu culling to cost Gauteng farm R65m - Fin24
11 Oct 2017 at 1:46am