avianinfluenza.org

Trial of Experimental Avian Influenza Vaccine

Updated: Friday, November 27, 2020 3:51 AM EDT
Avian influenza Articles
Preparing for Human, H5N1 bird flu outbreak
Bird flu symptoms
Can you catch Bird Flu , Avian Influenza from eating poultry?
Confirmed human H5N1 bird flu cases
The origins of Bird Flu
Your cat and Bird flu , avian influenza
Potential bird flu treatment discovery
Bird flu , Avian influenza, new Spanish flu of 1918?
Bird Flu scare and the US bird Embargo
Bird flu , Avian Influenza a non-technical view
Bird flu , Avian flu outbreaks (human to human) in North America
Bird flu , Avian Influenza virus in Smuggled Thai Eagles
Bird flu , Avian Influenza Mutation H5N1 Virus
H5N1 Bird flu , Avian Influenza human vaccine developments
Bird flu , Avian influenza, fact or fiction?
Economic and Social Impacts of Bird Flu , Avian Influenza
Preparing For Pandemic Influenza
Bird Flu , Avian Influenza FAQ
Trial of Experimental Bird Flu , Avian Influenza Vaccine
Bird flu , Avian Influenza infection in Humans
Bird Flu , Avian Influenza explained

Bird Flu Map Links
USGS Interactive Bird flu map
Whooper Swan Tracking Map
Bird flu - US Government

Trial of Experimental Avian Influenza Vaccine

March 2005

Fast-track recruitment has begun for a trial to investigate the safety of a vaccine against the H5N1 strain of avian influenza, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced today.

Sites in Rochester, NY, Baltimore and Los Angeles will enroll a total of 450 healthy adults. The clinical sites are part of the NIAID-sponsored Vaccine and Treatment Evaluation Units (VTEU).

“While there have been relatively few cases worldwide of H5N1 avian influenza infection in humans, the public health community is concerned that the H5N1 strain of avian influenza virus will develop the capability of efficiently spreading from human to human and thus create a risk for a worldwide pandemic,” says NIAID Director Anthony S. Fauci, M.D.

“NIAID has supported research on H5N1, the strain responsible for this deadly form of avian influenza, since 1997 when the first cases in humans were reported. The initiation of this vaccine trial marks a key advance in our efforts to prepare to respond to an avian influenza pandemic,” adds Dr. Fauci.

Sanofi pasteur, Swiftwater, PA, manufactured the trial vaccine, which is an inactivated vaccine made from an H5N1 virus isolated in Southeast Asia in 2004. Sanofi pasteur, formerly Aventis Pasteur, was awarded a contract by NIAID to manufacture the H5N1 vaccine in May 2004.

This Phase I trial will test the avian influenza vaccine’s safety and ability to generate an immune response in 450 healthy adults aged 18 to 64. If the vaccine is shown to be safe in adults, there are plans to test it in other populations, such as the elderly and children.

H5N1 avian influenza leads to severe disease in both birds and humans. Between January 2004 and March 11, 2005, there were 69 confirmed cases of and 46 deaths from H5N1 infection in humans reported to the World Health Organization. To date, there has been a small number of cases where human-to-human transmission of the virus may have occurred. However, public health experts fear that the virus may evolve into one that is more easily transmitted between people. If this were to happen, a worldwide pandemic could follow.

Influenza pandemics are global outbreaks that emerge infrequently and unpredictably and involve strains of virus to which humans have little or no immunity. H5N1 is one such Avian Influenza virus strain. The last influenza pandemic swept the globe in 1968; many public health officials believe the world is overdue for another one

EU poultry industry on edge as bird flu outbreaks spread - The Poultry Site
27 Nov 2020 at 3:15am
EU poultry industry on edge as bird flu outbreaks spread - The Poultry Site
27 Nov 2020 at 3:15am
Bird flu fears grow after spate of mysterious UK swan deaths - The Guardian
27 Nov 2020 at 2:48am
Bird flu fears grow after spate of mysterious UK swan deaths - The Guardian
27 Nov 2020 at 2:48am
China reports H5N8 bird flu in swans in Shanxi province: agriculture ministry...
26 Nov 2020 at 6:55pm
China reports H5N8 bird flu in swans in Shanxi province: agriculture ministry...
26 Nov 2020 at 6:55pm
Health News Roundup: Fast spreading bird flu puts EU poultry industry on edge...
26 Nov 2020 at 1:57pm
Health News Roundup: Fast spreading bird flu puts EU poultry industry on edge...
26 Nov 2020 at 1:57pm
Gravitas: Europe battles new outbreak of Bird Flu - WION
26 Nov 2020 at 11:04am
Gravitas: Europe battles new outbreak of Bird Flu - WION
26 Nov 2020 at 11:04am
1 million chickens to be culled after bird flu outbreak - Business Insurance
26 Nov 2020 at 8:27am
1 million chickens to be culled after bird flu outbreak - Business Insurance
26 Nov 2020 at 8:27am
Fast spreading bird flu puts EU poultry industry on edge - Successful Farming
26 Nov 2020 at 5:29am
Fast spreading bird flu puts EU poultry industry on edge - Successful Farming
26 Nov 2020 at 5:29am
Bird flu in Europe: Mass culling of chickens underway to stop outbreak - WION
26 Nov 2020 at 3:58am
Bird flu in Europe: Mass culling of chickens underway to stop outbreak - WION
26 Nov 2020 at 3:58am
OIE reports cases of H5N8 bird flu in Croatia - The Poultry Site
26 Nov 2020 at 1:49am
OIE reports cases of H5N8 bird flu in Croatia - The Poultry Site
26 Nov 2020 at 1:49am
Japan's bird flu outbreak spreads to third prefecture - The Poultry Site
26 Nov 2020 at 1:39am
Japan's bird flu outbreak spreads to third prefecture - The Poultry Site
26 Nov 2020 at 1:39am
Croatia reports highly pathogenic H5N8 bird flu on a farm - OIE - Successful ...
25 Nov 2020 at 10:31am
Croatia reports highly pathogenic H5N8 bird flu on a farm - OIE - Successful ...
25 Nov 2020 at 10:31am
Poland to cull more than 900000 hens amid new bird flu outbreak - PAP - Succe...
25 Nov 2020 at 10:08am
Poland to cull more than 900000 hens amid new bird flu outbreak - PAP - Succe...
25 Nov 2020 at 10:08am
Japan`s bird flu outbreak spreads, pathogenic avian influenza confirmed - WION
25 Nov 2020 at 4:38am
Japan`s bird flu outbreak spreads, pathogenic avian influenza confirmed - WION
25 Nov 2020 at 4:38am
Netherlands culls 190000 chickens as bird flu outbreak spreads - The Poultry ...
25 Nov 2020 at 1:40am
Netherlands culls 190000 chickens as bird flu outbreak spreads - The Poultry ...
25 Nov 2020 at 1:40am
Japan detects a new outbreak of bird flu - The Poultry Site
25 Nov 2020 at 1:27am
Japan detects a new outbreak of bird flu - The Poultry Site
25 Nov 2020 at 1:27am
'Highly contagious' strain of bird flu found in Weymouth goose - Dorset Echo
24 Nov 2020 at 5:10pm
'Highly contagious' strain of bird flu found in Weymouth goose - Dorset Echo
24 Nov 2020 at 5:10pm
Nearly 190000 chickens culled after bird flu outbreak - Business Insurance
24 Nov 2020 at 8:15am
Nearly 190000 chickens culled after bird flu outbreak - Business Insurance
24 Nov 2020 at 8:15am
2 bird flu clusters in the UK confirmed as highly pathogenic - The Poultry Site
24 Nov 2020 at 1:07am
2 bird flu clusters in the UK confirmed as highly pathogenic - The Poultry Site
24 Nov 2020 at 1:07am
S. Korea to ban free-range poultry through Feb. amid bird flu outbreak - The ...
23 Nov 2020 at 6:32pm
S. Korea to ban free-range poultry through Feb. amid bird flu outbreak - The ...
23 Nov 2020 at 6:32pm
Bird flu outbreak at Melton's Twinlakes theme park - BBC News
23 Nov 2020 at 9:38am
Bird flu outbreak at Melton's Twinlakes theme park - BBC News
23 Nov 2020 at 9:38am