avianinfluenza.org

Trial of Experimental Avian Influenza Vaccine

Updated: Wednesday, April 25, 2018 7:25 AM EDT
Avian influenza Articles
Preparing for Human, H5N1 bird flu outbreak
Bird flu symptoms
Can you catch Bird Flu , Avian Influenza from eating poultry?
Confirmed human H5N1 bird flu cases
The origins of Bird Flu
Your cat and Bird flu , avian influenza
Potential bird flu treatment discovery
Bird flu , Avian influenza, new Spanish flu of 1918?
Bird Flu scare and the US bird Embargo
Bird flu , Avian Influenza a non-technical view
Bird flu , Avian flu outbreaks (human to human) in North America
Bird flu , Avian Influenza virus in Smuggled Thai Eagles
Bird flu , Avian Influenza Mutation H5N1 Virus
H5N1 Bird flu , Avian Influenza human vaccine developments
Bird flu , Avian influenza, fact or fiction?
Economic and Social Impacts of Bird Flu , Avian Influenza
Preparing For Pandemic Influenza
Bird Flu , Avian Influenza FAQ
Trial of Experimental Bird Flu , Avian Influenza Vaccine
Bird flu , Avian Influenza infection in Humans
Bird Flu , Avian Influenza explained

Bird Flu Map Links
USGS Interactive Bird flu map
Whooper Swan Tracking Map
Bird flu - US Government

Trial of Experimental Avian Influenza Vaccine

March 2005

Fast-track recruitment has begun for a trial to investigate the safety of a vaccine against the H5N1 strain of avian influenza, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced today.

Sites in Rochester, NY, Baltimore and Los Angeles will enroll a total of 450 healthy adults. The clinical sites are part of the NIAID-sponsored Vaccine and Treatment Evaluation Units (VTEU).

“While there have been relatively few cases worldwide of H5N1 avian influenza infection in humans, the public health community is concerned that the H5N1 strain of avian influenza virus will develop the capability of efficiently spreading from human to human and thus create a risk for a worldwide pandemic,” says NIAID Director Anthony S. Fauci, M.D.

“NIAID has supported research on H5N1, the strain responsible for this deadly form of avian influenza, since 1997 when the first cases in humans were reported. The initiation of this vaccine trial marks a key advance in our efforts to prepare to respond to an avian influenza pandemic,” adds Dr. Fauci.

Sanofi pasteur, Swiftwater, PA, manufactured the trial vaccine, which is an inactivated vaccine made from an H5N1 virus isolated in Southeast Asia in 2004. Sanofi pasteur, formerly Aventis Pasteur, was awarded a contract by NIAID to manufacture the H5N1 vaccine in May 2004.

This Phase I trial will test the avian influenza vaccine’s safety and ability to generate an immune response in 450 healthy adults aged 18 to 64. If the vaccine is shown to be safe in adults, there are plans to test it in other populations, such as the elderly and children.

H5N1 avian influenza leads to severe disease in both birds and humans. Between January 2004 and March 11, 2005, there were 69 confirmed cases of and 46 deaths from H5N1 infection in humans reported to the World Health Organization. To date, there has been a small number of cases where human-to-human transmission of the virus may have occurred. However, public health experts fear that the virus may evolve into one that is more easily transmitted between people. If this were to happen, a worldwide pandemic could follow.

Influenza pandemics are global outbreaks that emerge infrequently and unpredictably and involve strains of virus to which humans have little or no immunity. H5N1 is one such Avian Influenza virus strain. The last influenza pandemic swept the globe in 1968; many public health officials believe the world is overdue for another one

Man involved in foiled attempt to smuggle 121 live birds jailed 8 months - Ch...
25 Apr 2018 at 3:26am
Man involved in foiled attempt to smuggle 121 live birds jailed 8 months - Ch...
25 Apr 2018 at 3:26am
Bird flu: FG spends N2.8bn as compensation to poultry farmers - Lagos (press ...
25 Apr 2018 at 12:52am
Bird flu: FG spends N2.8bn as compensation to poultry farmers - Lagos (press ...
25 Apr 2018 at 12:52am
'Bird flu-free' tag still 'iffy' as surveillance extended in hot zones - Busi...
24 Apr 2018 at 6:30am
'Bird flu-free' tag still 'iffy' as surveillance extended in hot zones - Busi...
24 Apr 2018 at 6:30am
Grey Heron, tagged for bird flu programme, sighted after 4 years in ... - The...
23 Apr 2018 at 9:58pm
Grey Heron, tagged for bird flu programme, sighted after 4 years in ... - The...
23 Apr 2018 at 9:58pm
BIRD FLU HIT NORTH WEST - Platinum Weekly (press release)
19 Apr 2018 at 7:53am
BIRD FLU HIT NORTH WEST - Platinum Weekly (press release)
19 Apr 2018 at 7:53am
Bird flu poses new threat to endangered African penguin - The Times
16 Apr 2018 at 4:01pm
Bird flu poses new threat to endangered African penguin - The Times
16 Apr 2018 at 4:01pm
South Africa: North West On Bird Flu Outbreak in Parts of the Province - AllA...
16 Apr 2018 at 8:53am
South Africa: North West On Bird Flu Outbreak in Parts of the Province - AllA...
16 Apr 2018 at 8:53am
Hong Kong pet bird market temporarily closed amid detection of bird flu virus...
14 Apr 2018 at 3:51am
Hong Kong pet bird market temporarily closed amid detection of bird flu virus...
14 Apr 2018 at 3:51am
3 bird flu cases confirmed in North West - Eyewitness News
13 Apr 2018 at 10:41am
3 bird flu cases confirmed in North West - Eyewitness News
13 Apr 2018 at 10:41am
Hong Kong's bird market to close for 21 days after avian flu virus found in s...
13 Apr 2018 at 9:05am
Hong Kong's bird market to close for 21 days after avian flu virus found in s...
13 Apr 2018 at 9:05am
Bird flu scare shuts down popular songbird garden in Hong Kong for 21 days - ...
13 Apr 2018 at 3:17am
Bird flu scare shuts down popular songbird garden in Hong Kong for 21 days - ...
13 Apr 2018 at 3:17am
Japan's 1st deadly mass avian flu infections among wild ground birds hits cro...
12 Apr 2018 at 1:02am
Japan's 1st deadly mass avian flu infections among wild ground birds hits cro...
12 Apr 2018 at 1:02am
Boulders Beach penguins fall victim to bird flu outbreak - News24
9 Apr 2018 at 10:18am
Boulders Beach penguins fall victim to bird flu outbreak - News24
9 Apr 2018 at 10:18am
Cameroon concerned about bird flu outbreak in Nigeria - Journalducameroun.com...
9 Apr 2018 at 2:46am
Cameroon concerned about bird flu outbreak in Nigeria - Journalducameroun.com...
9 Apr 2018 at 2:46am
Bird flu outbreak: Cameroon beefs up border security - Journalducameroun.com ...
7 Apr 2018 at 5:21am
Bird flu outbreak: Cameroon beefs up border security - Journalducameroun.com ...
7 Apr 2018 at 5:21am
Zim gets boost in war against bird flu, fall armyworm - The Herald
6 Apr 2018 at 3:13pm
Zim gets boost in war against bird flu, fall armyworm - The Herald
6 Apr 2018 at 3:13pm
Bird Flu: 16 more penguins die at Boulders Beach - Cape Business News
5 Apr 2018 at 5:54am
Bird Flu: 16 more penguins die at Boulders Beach - Cape Business News
5 Apr 2018 at 5:54am
Bulgaria reports H5N8 bird flu outbreak in duck farm - Reuters
5 Apr 2018 at 3:12am
Bulgaria reports H5N8 bird flu outbreak in duck farm - Reuters
5 Apr 2018 at 3:12am
New bird flu virus H6N2 comes to roost - Times of India
1 Apr 2018 at 10:52pm
New bird flu virus H6N2 comes to roost - Times of India
1 Apr 2018 at 10:52pm
Eggs recalled after bird flu outbreak [April Fools] - News24
31 Mar 2018 at 10:00pm
Eggs recalled after bird flu outbreak [April Fools] - News24
31 Mar 2018 at 10:00pm